Cycloastragenol is an aglycone of astragaloside IV. When astragalosides enters the human body, it produces cycloastragenol under the action of intestinal flora. Cycloastragenol is the key component of astragaloside’s pharmacological effects.
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Cycloastragenol is the only telomerase activator reported among natural products, which has pharmacological effects such as anti-aging, anti-apoptosis, anti-fibrosis, immune regulation, promoting cell proliferation and wound healing.
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We provide cycloastragenol with purity over 99%. Solvent residues and heavy metals meet the requirements of ICH for pharmaceutical raw materials. It can be safely used in medicine and health food.
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Specifications of Cycloastragenol
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Items |
Specifications |
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Characteristics |
White powder |
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Identification |
TLC Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â single spot |
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ESI-MS spectra              490.7(M+) |
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NMR spectra                typical signal |
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HPLC Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Retention time |
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|
Odor |
Neutral |
|
Loss on Drying |
≤1.0% |
|
Heavy metals |
Lead                     ≤0.5ppm |
|
Arsenic                   ≤1ppm |
|
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Cadmium                 ≤1ppm |
|
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Mercury                  ≤1ppm |
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Microbiological |
Total plate count          ≤1000 CFU/g |
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Yeast and Mold           ≤100 CFU/g |
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Enterobacteriaceae        ≤10 CFU/g |
|
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E. Coli                        Negative |
|
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Coliform                      Negative |
|
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Salmonella                    Negative |
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Staphylococcus                 Negative |
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Pseudomonas Aeruginosa         Negative |
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|
Assay  |
≥98.5% by HPLC (As Is Basis) |
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Residual solvents |
Methanol  ≤3000ppm |
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Acetone  ≤5000ppm |
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Ethanol   ≤5000ppm |
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DCM     ≤600ppm |
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